Description
Product Characteristics:
Aliases: hUbc12 antibody, NEDD8 carrier protein antibody, NEDD8 conjugating enzyme Ubc12 antibody, NEDD8 protein ligase antibody, NEDD8-conjugating enzyme Ubc12 antibody, UBC-RS2 antibody, UBC12 antibody, UBC12_HUMAN antibody, ube2m antibody, ubiquitin carrier protein M antibody, Ubiquitin conjugating enzyme E2 M antibody, Ubiquitin-conjugating enzyme E2 M antibody, ubiquitin-protein ligase M antibody, yeast UBC12 homolog antibody
Target Information: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq, Jul 2008]